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Ebola: The Challenging Road to Recovery

thelancet.com - Michael Edelstein, Philip Angelides, David L Heymann - February 8, 2015
DOI: http://dx.doi.org/10.1016/S0140-6736(15)60203-3

The resurgence of polio in Syria in 2013 has shown how a breakdown in public health can lead to the re-emergence of previously well-controlled diseases. In 2014 and early 2015 Liberia, Guinea, and Sierra Leone have focused all resources on the Ebola response at the expense of other health programmes. Combined with losing a large proportion of the health-care workforce and the population's reluctance to attend health-care facilities for fear of Ebola, this means the three countries are now at increased risk of other diseases that their health programmes usually target.

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Redesign Of Ebola Treatment Units Draws 1500 Innovations, Including Locally

INTELLECTUAL PROPRERTY WATCH  by Hillary Muheebwa                                                    March 16, 2015

KAMPALA, UGANDA – In light of the persistence of the Ebola outbreak and the demands it has placed on global infection containment resources and processes, the United States government disaster response community recognised an opportunity to use open innovation to make significant strides in advancing the ability to combat Ebola. The results include a local success story.

 

“The United States Agency for International Development [USAID], in partnership with the White House Office of Science and Technology Policy, the Centers for Disease Control and Prevention, and the Department of Defense, created a Grand Challenge for Development to target Ebola because we faced the largest epidemic of this disease in history,” said Caroline Pepek, spokeswoman, USAID US Global Development Laboratory....

One of the chosen ideas is the next generation ergonomic tent design submitted by ResilientAfrica Network (RAN) and Makerere University, in Kampala, Uganda.

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Ebola vaccine trial to combine GSK, Emergent Bio shots

REUTERS                                                                                                          March 16, 2015

LONDON  - Scientists are to test a new two-shot Ebola vaccine using an experimental shot from Britain's GlaxoSmithKline, which is already in clinical trials in Africa, and a new kind of booster from Emergent BioSolutions.

A health worker, left, injects a man in his arm with an Ebola vaccine in Conakry, Guinea, March 7, 2015. The World Health Organization is starting large-scale testing of an experimental Ebola vaccine in Guinea  to see how effective it might be in preventing future outbreaks of the deadly virus.  (AP Photo/ Youssouf Bah)

The Maryland-based biotech company said on Monday its modified vaccinia Ankara (MVA) Ebola Zaire vaccine would be used in an initial Phase I clinical study to be conducted by researchers at the University of Oxford.

Although Ebola case numbers have fallen to a low level, drug companies are still pushing ahead with efforts to develop an effective vaccine, which may help fight the next outbreak, even if it does not come in time for the current epidemic.

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A Life-Saving Comic: Educating Children in West Africa about Ebola

BIOSECTOR PRESS  by Chris Shilling                    March 9, 2015

As efforts intensify at all levels by international health organisations and on the ground by community health workers in providing treatment, supplies and preventive measures,  young people and children – perhaps the ones most affected – need to have access to good health education resources to help them better understand both the medical and health aspects of Ebola.

To address this issue, Afrelib is working in partnership with Medikidz, (http://www.medikidz.com/gb-en/) the world’s first medical information company aimed at children, to produce learning material in an interactive, comic book format. With this health education comic, it should be possible to provide easy-to-understand and engaging information so that it not only helps in disseminating good preventive measures as recommended by public health organisations but also helps them in dealing with the cultural and social issues surrounding this epidemic.

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Watch closely and explain frequently: Liberia's Ebola lessons

REUTERS   By James Harding Giahyue and Emma Farge                                                   March 13, 2015

MONROVIA/DAKAR - Seven months after Ebola paralysed Liberia's capital, Friday marked 21 days since the country registered a case of the virus - offering lessons to its neighbors on the importance of surveillance and education in beating the deadly epidemic....

 A massive influx of international aid, including crucial U.S. military assistance, helped Liberia to turn the tide of the outbreak.

But, notes Tariq Riebl, Oxfam's Ebola response manager in Liberia, "What got us to the endgame is that communities took things into their own hands...."

Read complete story.
http://news.yahoo.com/watch-closely-explain-frequently-liberias-ebola-lessons-184507811.html;_ylt=AwrBJR6EmAVV3D0AbnTQtDMD

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Exclusive: take a first look at the next generation ebola-protection suit

QUARTZ  by Grace Dobush                                         March 13, 2015

AUSTIN, Texas—Perhaps the most surprising and important product debuting at SXSW Interactive this year is a personal protective equipment (PPE) prototype for health care workers dealing with Ebola, a tangible result of the U.S. government adapting the culture of innovation and design thinking so key in the startup world.

A team from the U.S. Agency for International Development demonstrated the traditional Ebola suit and the new suit in a preview for Quartz....

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Vaccines Face Same Mistrust That Fed Ebola

NEW YORK TIMES  by and         March 14, 2015

MONROVIA, Liberia — West Africa’s Ebola epidemic may be waning, but another outbreak in the future is a near certainty, health officials say.

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Lack of Ebola Cases Shifts Vaccine Trials Away From Liberia

TIME MAGAZINE  by Alexandra Sifferlin                                                                        March 13, 2015

The National Institutes of Health (NIH) may relocate its clinical trials of Ebola vaccines to Guinea, since there are no longer enough Ebola cases in Liberia for a proper efficacy trial.

On Feb. 2, the NIH launched an initial safety trial for two vaccines to protect against Ebola in Liberia. The plan was to test 600 people for overall safety and then launch a second phase of the trial in 27,000 people to see whether or not the vaccine prevents infection with Ebola virus compared to a placebo.

The safety test was successfully completed the week of March 9—but around the same time, Liberia announced that it had released its last confirmed patient from its Ebola treatment centers. ...

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The hidden cost of Ebola: thousands of measles deaths

VOX  by Julia Belluz                                            March 12, 2015

(Scroll down for full Science Journal study.)

As if being stricken by the most deadly virus known to man weren't enough, now, it seems, West Africa is on alert for outbreaks of vaccine-preventable diseases including measles, whooping cough, and tuberculosis.

A girl collects her family's laundry after drying it on a rooftop in the West Point township on January 31, 2015 in Monrovia, Liberia. Life has been disrupted by Ebola for many Liberians.

In a new study in the journal Science, researchers focused on measles — the most contagious virus recorded — and applied statistical models to quantify the likelihood of an epidemic in the three countries worst hit by Ebola, Liberia, Sierra Leone, and Guinea.

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The hidden cost of Ebola: thousands of measles deaths

VOX  by  Julia Belluz                                           March 12, 2015

(Scroll down for Science journal study.)

As if being stricken by the most deadly virus known to man weren't enough, now, it seems, West Africa is on alert for outbreaks of vaccine-preventable diseases including measles, whooping cough, and tuberculosis.

A girl collects her family's laundry after drying it on a rooftop in the West Point township on January 31, 2015 in Monrovia, Liberia. Life has been disrupted by Ebola for many Liberians.

In a new study in the journal Science, researchers focused on measles — the most contagious virus recorded — and applied statistical models to quantify the likelihood of an epidemic in the three countries worst hit by Ebola, Liberia, Sierra Leone, and Guinea.

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