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Health - West Africa MPHISE

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This working group is focused on discussions about health within the West Africa MPHISE.

The mission of this working group is to focus on discussions about health within the West Africa MPHISE.

Members

evakee John.R.Falco.VMD Kathy Gilbeaux mdmcdonald MDMcDonald_me_com Ozoneac

Email address for group

health_westafrica_mphise@m.resiliencesystem.org

Zika - Information, FAQs and Research

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An expanding list of information resources on Zika virus . . .

CDC - Zika Virus - Case Counts in the US
https://www.cdc.gov/zika/geo/united-states.html

CDC - Zika Virus - Timeline of "What's New"
http://www.cdc.gov/zika/whats-new.html

CDC Newsroom Releases
http://www.cdc.gov/media/archives.htm

Nigeria Hit by Unprecedented Lassa Fever Outbreak

           

This year, the rats that carry Lassa fever may be more numerous, or more likely to harbor the virus.  Photo: Reuters/Stringer

CLICK HERE - reliefweb - Nigeria: Lassa Fever Outbreak

CLICK HERE - WHO - Nigeria - Lassa Fever

science.sciencemag.org - by Leslie Roberts - March 16, 2018

By early January, it was clear something “really, really extraordinary” was going on in Nigeria, says Lorenzo Pomarico of the Alliance for International Medical Action (ALIMA). Cases of Lassa fever, a rare viral hemorrhagic disease, were skyrocketing across the country—more were recorded in the first 2 months of 2018 than in any previous year. Unprepared for a disease that has no vaccines or drugs and kills 20% to 30% of those it sickens, eight health care workers were infected early on and three died. “Something was going very wrong with the outbreak,” Pomarico says.

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Ebola Had Significant Collateral Damage to Liberians' Health

           

A mural announces anti-Ebola sentiment outside a business in Harper, Liberia.  Brad Wagenaar

CLICK HERE - STUDY - The 2014–2015 Ebola virus disease outbreak and primary healthcare delivery in Liberia: Time-series analyses for 2010–2016

After the 2014 outbreak, the population's needs were often unmet in terms of primary care, mother-child health, and immmunizations.

newsroom.uw.edu - by Ashlie Chandler - February 20, 2018

The 2014 Ebola outbreak in West Africa rapidly became the deadliest occurrence of the disease — claiming 4,809 lives in Liberia alone.  Now new research from the University of Washington suggests Ebola's collateral effects on that nation's health system likely caused more deaths than Ebola did directly.

The study, published today in PLOS Medicine, found that it only took four months for Liberia to lose between 35 percent and 67 percent of primary health care services after the  Ebola outbreak began.

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Forty Years Later, Ebola Survivors are Still Making Antibodies to the Lethal Virus

           

Lab technician and Ebola survivor Sukato Mandzomba (front) worked with Peter Piot (back) in 1976 and again in 2016.  Heidi Larson

CLICK HERE - STUDY - Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection

sciencemag.org - by Jon Cohen - December 14, 2017

Forty years after the first documented Ebola outbreak, some of the survivors still have antibodies against the virus, a new study reveals. The find bolsters the widely held assumption that Ebola survivors remain immune to the virus for life. The work may also help guide development of new medicines and clarify the long-term health consequences of an Ebola infection.

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Where Does the Ebola Virus Hide Between Outbreaks?

           

Photo by Steve Babuljak

ucsf.edu - by Samantha Ancona Esselmann, Samantha Hindle and Ben Mansky - October 24, 2017

Joe DeRisi, PhD, is a master detective of infectious diseases. No matter how obscure or complex, he says he’ll take on the challenge because “it could lead to new biology that we wouldn’t have discovered otherwise.”

That's precisely what happened when he stumbled on a clue to cracking the decades-long search for the place – or creature – where the Ebola virus hides between deadly outbreaks. . . .

 . . . In 2009, DeRisi began studying an incurable disease that was killing reptiles raised in captivity, a disease that caused strange neurological symptoms ranging from vomiting to uncontrollable contortions. They found the culprit – a previously undescribed arenavirus – and uncovered something surprising: the Arenavirus’s glycoprotein, a viral “access badge” to the secure insides of a cell, actually belonged to the Ebola virus.

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Ebola May Linger in Men's Semen for More Than 2 Years

Particles of Ebola virus (Zaire) obtained from cell culture fluid.  Credit: Elena Ryabchikova, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Science

CLICK HERE - STUDY - Ebola Virus RNA Detection in Semen More than Two Years After Resolution of Acute Ebola Virus Infection

livescience.com - by Tia Ghose - August 1, 2017

Ebola may linger in men's semen for more than two years, a new study suggests.

What's more, at least one man who survived Ebola and then tested negative for the presence of the virus in his semen later tested positive, the new study found.

The findings raise questions about how long Ebola can linger in special immune hideouts in the body.

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Liberia - 9 Persons Die Mysteriously In Sinoe County

gnnliberia.com - by Cholo Brooks - April 25, 2017

Police in Sinoe County, southeastern Liberia, are investigation the mysterious death of nine persons after a repass of one late Edwin Dunbar, former Proprietor of One Family Entertainment Center who died few weeks ago in Greenville following a 2-night wake keeping.

According to our contact, those who died mysteriously include five females and four males, our contact said specimens from the nine deceased have been taken to Buchanan, Grand Bassa County for testing to establish the actual cause of death.

As a result of this terrible incident, officers of the Liberia National Police have been deployed in the streets of Greenville using mega phones and requesting those who ate the repass to report themselves.

Our contact said the strange and disturbing situation has created panic among citizens of the County, with others leaving for their towns and villages for fear of the unexpected.

County Health Officer John Logan when asked by our contact to speak on this prevailing situation, as to what is responsible for the mysterious deaths declined to comment on the issue.

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Huge Genome Study Dissects Ebola Outbreak's Spread

NSAID / Flickr

CLICK HERE - Nature - Virus genomes reveal factors that spread and sustained the Ebola epidemic

cidrap.umn.edu - Lisa Schnirring - April 14, 2017

The largest genome sample ever analyzed for a human epidemic reveals that the West Africa epidemic unfolded with small, overlapping outbreaks as the virus spread over short distances and that urban settings amplified the spread.

Meanwhile, another study harnessed different advanced scientific tools in the blood of a single sick patient to detail gene-level response during infection.

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CLICK HERE - Science Translational Medicine - Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease

 

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