REUTERS                                                    March 18, 2015

WASHINGTON ==The U.S. Food and Drug Administration said an advisory panel will discuss the development of Ebola vaccines, days after an American health worker was flown back after being tested positive for Ebola in Sierra Leone.

The federal health regulator would discuss the development of vaccines on May 12, it announced on its website on Wednesday.

The resurgence of the virus last year prompted drugmakers from across the world to develop new treatments that are in different stages of studies....

The World Health Organization said it will decide on mass vaccination against the virus in August.

See full story.

http://www.reuters.com/article/2015/03/18/us-health-ebola-fda-idUSKBN0ME1D520150318
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See Federal Register notice of meeting.

https://www.federalregister.gov/articles/2015/03/17/2015-06116/vaccines-and-related-biological-products-advisory-committee-notice-of-meeting

LIVE SCIENCE by Rachel Rattner                                                                                 March 18, 2015

Health officials have made tremendous progress in fighting the Ebola epidemic in West Africa in recent months, but continued efforts are still needed, experts say. That's because the cases that are happening now could be enough to restart the whole epidemic....

Although health officials are trying to trace all of the people who had contact with each Ebola patient, this "contact tracing" is far from perfect in Guinea and Sierra Leone. As a result, cases pop up among people who officials didn't know were at risk. For example, so far this month, just 14 percent of cases in Guinea occurred among people who were known to have had contact with someone who was sick with Ebola, WHO says.

This "shadow epidemic," which is occurring under the radar, is very worrisome, said Dr. Amesh Adalja, a senior associate and infectious disease physician at the Center for Health Security at the University of Pittsburgh.

If this shadow transmission continues, "it will threaten to cause this whole outbreak to reignite again," Adalja said. "You have to make sure you're finding every case, and stopping transmission in every case."

The Ebola Crisis Was Terrible. But Next Time Could Be Much Worse.

NEW YORK TIMES OPINION PAGE by Bill Gates                                                           March 18, 2015

(Scroll down for fuller Bill Gates article in the New England Journal of Medicine)

SEATTLE — The Ebola epidemic in West Africa has killed more than 10,000 people. If anything good can come from this continuing tragedy, it is that Ebola can awaken the world to a sobering fact: We are simply not prepared to deal with a global epidemic.

NEW YORK TIMES  by Sheri Fink, MD                                                           March 17, 2015
    
The latest American aid worker to contract Ebola overseas, last week in Sierra Leone, was swiftly evacuated to a specialized treatment center for infected health workers run by the British Defense Ministry in the country’s capital, Freetown, then on to the National Institutes of Health clinical center in Bethesda, Md. Doctors at the center said Monday that his condition had worsened from serious to critical since his arrival on Friday.

DEVEX   by Richard Jones                                                         March 17, 2015

(scroll down for link to EU statement.)

As the death toll from Ebola now tops 10,000 in West Africa, donors and aid implementers are figuring out how to best transition from the emergency to the recovery phase of the crisis.

Top EU and U.N. officials, leaders of Ebola-affected nations and representatives from the African Union, nongovernmental organizations, the private sector and the scientific community met in Brussels, Belgium, earlier this month to make progress on this goal. They agreed to embark on the design of a road map to help the economies of Guinea, Sierra Leone and Liberia get back on track, starting with the priority task of rebuilding health systems.

But that, of course, will be no easy feat.

“We are at a really crucial stage of the real fight against Ebola, because this is a turning point when the emergency stage or the emergency response or medical response to Ebola containment is now turning into coordinating and structuring the long-term recovery program,” European Commissioner for International Cooperation and Development Neven Mimica said in an exclusive interview with Devex at the Palais d’Egmont in Brussels.

REUTERS   by Saliou Samb and Emma Farge                                            March 17, 2015

CONAKRY/DAKAR - Guinea has suffered a setback in its fight against Ebola with a rash of new cases, including three doctors infected by the virus, with officials blaming weak surveillance and a failure to follow safety procedures.

  ... Guinea has seen cases rise for three consecutive weeks, according to World Health Organization data.

A government health report from the weekend showed there were 21 new cases in a single day, a spike from the recent daily average of eight.

One big source of concern is a chain of new infections that can be linked back to a woman who died of Ebola and was not buried safely, according to Fatoumata Lejeune-Kaba, spokeswoman for the U.N.'s Ebola emergency response mission UNMEER.

"It's a major setback .... It's due to individual behaviours. That is having a devastating effect on the community. People are simply not practising the safety rules that we have been talking about for a year," she told Reuters.

Read complete story.

http://news.yahoo.com/guinea-ebola-cases-rise-three-doctors-infected-144134152.html;_ylt=AwrBEiI_RghV8UgA.EnQtDMD

For communities, for children, for the future

UNICEF                                                                                                             March 16, 2015

As slight hints of recovery begin to surface in West Africa, UNICEF is looking at the impact of Ebola on children and the response and work of the affected communities in the report, Ebola: Getting to zero – for communities, for children for the future.

 The document traces some of the outbreak’s history along with the stories of survivors, health care workers and those working to make things better on the ground. The report also helps map out the actions that urgently must continue to help build resiliency and resuscitate basic services and systems decimated by Ebola.

Read the report

http://www.unicef.org/emergencies/ebola/files/EbolaReport.pdf

Also see additional information in the links below:

NEW YORK TIMES  by Pam Belluck                           March. 17, 2015

Last fall, with the Ebola epidemic raging, the small nation of Benin, a few countries away from the outbreak zone, experienced a cluster of unexplained deaths.

In mid-October, a 12-day-old baby was taken to a hospital in Tanguiéta, in northwest Benin, and died two days later. By early November, three employees of the hospital, St. Jean de Dieu, were dead too.

thelancet.com - Michael Edelstein, Philip Angelides, David L Heymann - February 8, 2015
DOI: http://dx.doi.org/10.1016/S0140-6736(15)60203-3

The resurgence of polio in Syria in 2013 has shown how a breakdown in public health can lead to the re-emergence of previously well-controlled diseases. In 2014 and early 2015 Liberia, Guinea, and Sierra Leone have focused all resources on the Ebola response at the expense of other health programmes. Combined with losing a large proportion of the health-care workforce and the population's reluctance to attend health-care facilities for fear of Ebola, this means the three countries are now at increased risk of other diseases that their health programmes usually target.

(READ COMPLETE ARTICLE) 

INTELLECTUAL PROPRERTY WATCH  by Hillary Muheebwa                                                    March 16, 2015

KAMPALA, UGANDA – In light of the persistence of the Ebola outbreak and the demands it has placed on global infection containment resources and processes, the United States government disaster response community recognised an opportunity to use open innovation to make significant strides in advancing the ability to combat Ebola. The results include a local success story.

“The United States Agency for International Development [USAID], in partnership with the White House Office of Science and Technology Policy, the Centers for Disease Control and Prevention, and the Department of Defense, created a Grand Challenge for Development to target Ebola because we faced the largest epidemic of this disease in history,” said Caroline Pepek, spokeswoman, USAID US Global Development Laboratory....

One of the chosen ideas is the next generation ergonomic tent design submitted by ResilientAfrica Network (RAN) and Makerere University, in Kampala, Uganda.

REUTERS                                                                                                          March 16, 2015

LONDON  - Scientists are to test a new two-shot Ebola vaccine using an experimental shot from Britain's GlaxoSmithKline, which is already in clinical trials in Africa, and a new kind of booster from Emergent BioSolutions.

A health worker, left, injects a man in his arm with an Ebola vaccine in Conakry, Guinea, March 7, 2015. The World Health Organization is starting large-scale testing of an experimental Ebola vaccine in Guinea  to see how effective it might be in preventing future outbreaks of the deadly virus.  (AP Photo/ Youssouf Bah)

The Maryland-based biotech company said on Monday its modified vaccinia Ankara (MVA) Ebola Zaire vaccine would be used in an initial Phase I clinical study to be conducted by researchers at the University of Oxford.

Although Ebola case numbers have fallen to a low level, drug companies are still pushing ahead with efforts to develop an effective vaccine, which may help fight the next outbreak, even if it does not come in time for the current epidemic.

BIOSECTOR PRESS  by Chris Shilling                    March 9, 2015

As efforts intensify at all levels by international health organisations and on the ground by community health workers in providing treatment, supplies and preventive measures,  young people and children – perhaps the ones most affected – need to have access to good health education resources to help them better understand both the medical and health aspects of Ebola.

To address this issue, Afrelib is working in partnership with Medikidz, (http://www.medikidz.com/gb-en/) the world’s first medical information company aimed at children, to produce learning material in an interactive, comic book format. With this health education comic, it should be possible to provide easy-to-understand and engaging information so that it not only helps in disseminating good preventive measures as recommended by public health organisations but also helps them in dealing with the cultural and social issues surrounding this epidemic.

REUTERS   By James Harding Giahyue and Emma Farge                                                   March 13, 2015

MONROVIA/DAKAR - Seven months after Ebola paralysed Liberia's capital, Friday marked 21 days since the country registered a case of the virus - offering lessons to its neighbors on the importance of surveillance and education in beating the deadly epidemic....

 A massive influx of international aid, including crucial U.S. military assistance, helped Liberia to turn the tide of the outbreak.

But, notes Tariq Riebl, Oxfam's Ebola response manager in Liberia, "What got us to the endgame is that communities took things into their own hands...."

Read complete story.
http://news.yahoo.com/watch-closely-explain-frequently-liberias-ebola-lessons-184507811.html;_ylt=AwrBJR6EmAVV3D0AbnTQtDMD

QUARTZ  by Grace Dobush                                         March 13, 2015

AUSTIN, Texas—Perhaps the most surprising and important product debuting at SXSW Interactive this year is a personal protective equipment (PPE) prototype for health care workers dealing with Ebola, a tangible result of the U.S. government adapting the culture of innovation and design thinking so key in the startup world.

A team from the U.S. Agency for International Development demonstrated the traditional Ebola suit and the new suit in a preview for Quartz....

NEW YORK TIMES  by NORIMITSU ONISHI and SHERI FINK        March 14, 2015

MONROVIA, Liberia — West Africa’s Ebola epidemic may be waning, but another outbreak in the future is a near certainty, health officials say.