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CDC - Ebola Virus RNA Stability in Human Blood and Urine in West Africa’s Environmental Conditions

cdc.gov

Janvier F, Delaune D, Poyot T, Valade E, Mérens A, Rollin PE, et al.

CLICK HERE - Ebola virus RNA stability in human blood and urine in West Africa’s environmental conditions
Emerg Infect Dis. 2016 Feb. http://dx.doi.org/10.3201/eid2202.151395

DOI: 10.3201/eid2202.151395

Abstract

We evaluated RNA stability of Ebola virus in EDTA blood and urine samples collected from infected patients and stored in West Africa’s environmental conditions. In blood, RNA was stable for at least 18 days when initial cycle threshold values were <30, but in urine, RNA degradation occurred more quickly.

 

 

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Ebolavirus Evolution: Past and Present

PLOS PATHOGENS  by Marc-Antoine de La Vega,  Derek Stein, and GaryKopinger, University of Manitoba, Canada , Nov. 12, 2015    

Winnipeg, Manitoba, Canada The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV) has now been around for almost 50 years. In this review, we discuss past and present outbreaks of EBOV and how those variants evolved over time. We explore and discuss selective pressures that drive the evolution of different Ebola variants, and how they may modify the efficacy of therapeutic treatments and vaccines currently being developed. Finally, given the unprecedented size and spread of the outbreak, as well as the extended period of replication in human hosts, specific attention is given to the 2014–2015 West African outbreak variant (Makona).

Read complete article.

http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005221

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To Prevent Malaria in Humans, Scientists Try Protecting Pigs

 New York TImes, November 2, 2015

http://www.nytimes.com/2015/11/03/health/to-prevent-malaria-in-humans-scientists-try-protecting-pigs.html?_r=1&WT.mc_id=SmartBriefs-Newsletter&WT.mc_ev=click

 

 

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Broken Healthcare Services: Pre Ebola Failures Persist

inprofiledaily.com - by mulbah - October 13, 2015

. . . “Dispatches made to health facilities are also being traced for evidence of delivery and receipts and preliminary results are showing that commodities were not received by health facilities as verified by documentation.”

Liberia has not only suffered the lack of essential drugs and medical supplies including quality health facilities to provide needed services to its citizenry over the years, but it has equally suffered the insincerity of people entrusted to manage and control procured drugs and medical supplies intended to prevent and combat diseases in the country.

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WHO - Ebola - Situation Reports - Interagency Collaboration on Ebola

                    

                                                   who.int                                                       ebolaresponse.un.org

Ebola Situation Reports:

CLICK HERE -WHO - Ebola Situation Report - 28 October 2015

CLICK HERE -  Interagency Collaboration on Ebola - Situation Report - 21 October 2015 (7 page .PDF report)

CLICK ON THE LINKS BELOW - WHO - Report Archives
http://apps.who.int/ebola/ebola-situation-reports
http://apps.who.int/ebola/ebola-situation-reports-archive
http://www.who.int/csr/disease/ebola/situation-reports/archive/en/
http://apps.who.int/gho/data/node.ebola-sitrep

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Ebola Returns: 2nd Case of Relapse Raises Questions

A microscopic view of the Ebola virus. Credit: CDC/Cynthia Goldsmith/Public Health Image LibraryImage: A microscopic view of the Ebola virus. Credit: CDC/Cynthia Goldsmith/Public Health Image Library

livescience.com - October 20th, 2015 - Ashley P. Taylor

Scottish nurse Pauline Cafferkey — who became sick with Ebola about a year ago and recovered, but then became very ill again last week with what may be a relapse of the deadly virus — is now improving.

"Pauline Cafferkey's condition has improved to serious but stable," representatives from London's Royal Free Hospital said in a statement Monday (Oct. 19).

Hospital representatives said on Oct. 9 that the nurse had developed an "unusual late complication" of the virus, and reported last week that she was "critically ill."

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Mystery Deaths in Sierra Leone Spread Fear of Ebola Relapses

submitted by George Hurlburt

      

Sierra Leonean doctors practice wearing protective clothing in the Ebola Training Academy in Freetown, Sierra Leone, December 16, 2014. Reuters

uk.reuters.com - by Kemo Cham and Emma Farge - October 21, 2015

. . . the case of Scottish nurse Pauline Cafferkey – the first known Ebola survivor to have an apparently life-threatening relapse – has revived concerns about the health of some 17,000 survivors in Sierra Leone, neighbouring Guinea and Liberia.

Doctors and health officials in Sierra Leone told Reuters that a handful of mystery deaths among discharged patients may also be types of Ebola relapses, stirring fear that the deadly virus may last far longer than previously thought in the body, causing other potentially lethal complications.

Diagnoses have not been made, partly because of a lack of relevant medical training and insufficient equipment for detecting a virus that can hide in inaccessible corners of the body - such as the spinal fluid or eyeball. In Cafferkey's case, the virus in her brain caused meningitis.

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Ebola outbreak in West Africa 22 months on: Key issues for recovery and preparedness, October 2015

                                                                     

acaps.org

Ebola Project, Thematic Report: Key issues for recovery and preparedness, Oct 2015 (3 page .PDF file)
http://acaps.org/img/documents/e-acaps-ebola-project-thematic-report-key-issues-for-recovery-and-preparedness-oct-2015.pdf

ACAPS - Thematic Reports
http://acaps.org/en/pages/ebola-project-sep-dec-2015-thematic-reports

 

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