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Last Ebola Patient Is Released in Liberia

ASSOCIATED PRESS by JONATHAN PAYE-LAYLEH                                             March 5, 2015

MONROVIA -- Liberia released its last Ebola patient, a 58-year old English teacher, from a treatment center in the capital on Thursday, beginning its countdown to being declared Ebola free.

"I am one of the happiest human beings today on earth because it was not easy going through this situation and coming out alive," Beatrice Yardolo told The Associated Press after her release.

...The St. Paul's Bridge community where she resides and teaches had become the last "hotspot" for Ebola cases in Monrovia, according to Tolbert Nyenswah, Assistant Health Minister and head of the country's Ebola response.

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Case Study: Nebraska's Ebola isolation and decontamination approach

MEDICAL NEWS TODAY                                                                                                 March 4, 2015

The Nebraska Biocontainment Unit (NBU), located at the Nebraska Medical Center, has shared its protocol for Ebola patient discharge, handling a patient's body after death and environmental disinfection in the March issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

Discharge process for a patient treated for EVD

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Ebola: Epidemic is not over – key areas still need to be tackled

Description of key Ebola areas---MSF

MSF                                                        March 3, 2015

The Ebola outbreak in West Africa continues, albeit with decreasing intensity. The virus has infected more than 23,700 people across the region since the outbreak was declared 11 months ago. While the number of new patients in Liberia is declining, numbers are still fluctuating in both Guinea and Sierra Leone. A total of 99 new confirmed cases were reported across the three worst affected countries during the week up to 22 February 2015.

The unpredictable nature of the epidemic means that teams from Médecins Sans Frontières/Doctors Without Borders (MSF) are maintaining a flexible approach and continuing to respond where the needs are greatest in Guinea, Liberia and Sierra Leone.

See country-by-country analysis and complete story.

http://www.msf.org/article/ebola-epidemic-not-over-%E2%80%93-key-areas-still-need-be-tackled

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Ebola: UN tells Brussels meeting world must ‘stay on course’ to get to, remain at zero cases

UNITED NATIONS NEWS CENTRE                           March 4, 2015

BRUSSELS --Representatives of United Nations organizations engaged in the response against Ebola pledged their support Ttuesday to the worst-affected West African countries in “each stage of this journey; the drive to zero, the early recovery, the medium and longer term development.”

UN and EU meet in Brussels, Belgium, to take stock of the Ebola situation and identify ways forward. Photo: UNMEER

The pledge was made at a high-level international conference on Ebola sponsored by the European Union in Brussels, Belgium, aimed at maintaining global attention on the crisis, taking stock of the fight against the epidemic and on coordinating next steps and discussing the recovery process.

The UN Secretary-General’s Special Envoy on Ebola, Dr. David Nabarro, said that current phase of the response “is the hardest part and a bumpy road” and urged the international community to remain fully engaged until the task is completed, especially as the virus is moving and as some communities are reticent about being engaged in the response.

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Ebola-hit countries seek help to repair their economies

REUTERS by Adrian Croft                                                                                     March 3, 2015
BRUSSELS - The three West African states hardest hit by the Ebola outbreak asked for help from donors on Tuesday to repair the damage to their economies now that the epidemic seems to be waning.

Leaders of Guinea, Liberia and Sierra Leone voiced confidence at a major international conference on the Ebola outbreak in Brussels that they were winning the battle but said they must remain focused on stamping out new infections....

International donors have pledged nearly $5 billion to help combat the Ebola outbreak, according to EU officials, although only about half of that has been disbursed so far.....

 The World Bank has estimated the epidemic will cost the three countries at least $1.6 billion in lost economic growth this year, or more than 12 percent of their combined output.

Read complete story.

http://news.yahoo.com/ebola-hit-countries-seek-help-repair-economies-161332797.html;_ylt=AwrBJR6.3_VUSjIA7pzQtDMD

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ZMapp Ebola Trial Starts In Liberia: Is It Too Late?

FORBES   by   David Kroll                                                                                          March 1, 2015

The widely-discussed antibody cocktail, ZMapp, is finally going to be tested under standardized, controlled conditions for its safety and efficacy in Ebola virus disease-infected patients in Liberia and, potentially, the United States.

Late Friday, the NIH National Institute of Allergy and Infectious Disease (NIAID) announced the launch of a randomized trial in up to 200 patient volunteers with confirmed Ebola virus infections.

The two-arm study will compare supportive standard of care with or without three intravenous infusions of ZMapp spaced three days apart. This is the same dosing regimen published in Nature that protected 18 of 18 monkeys when given up to five days after experimental infection.

LeafBio, the commercial arm of San Diego-based Mapp Biopharmaceutical, announced concomitantly that the FDA had approved their IND for this trial. The three antibodies that comprise ZMapp target both distinct and overlapping parts of the Ebola virus glycoprotein (GP) that it uses to infect humans.

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Thoughts turn to recovery as Ebola slowly ebbs in West Africa

 REUTERS By Daniel Flynn, James Harding Giahyue and Saliou Samb                              Feb. 27, 2015

 DAKAR/MONROVIA/CONAKRY - In the marble atrium of the Mammy Yoko hotel in Freetown, manager Nuno Neves has spotted something he has not seen since the Ebola virus struck Sierra Leone nine months ago: foreign businessmen.

The Radisson Blu chain opened the four-star hotel in April to cater for investors in one of Africa's fastest-growing economies. A month later, Ebola crossed the border from Guinea and those investors fled....

For months, Sierra Leone was cut off from the world amid panic at the worst recorded outbreak of the hemorrhagic fever, which has killed more than 9,500 people in Sierra Leone, Guinea and Liberia and infected over 23,500.

But with infection rates slowly declining, investors have begun to talk about post-Ebola reconstruction. Neves has noted the return of businessmen not seen since the hotel opened.

"They don't bring their teams. They just come to see what is going on and then they leave," he said, adding that 'business as usual' remains far off. "This will be a year focused on Ebola. First the fight to end Ebola and then reconstruction...."

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The Socio-Economic Impacts of Ebola in Liberia

      

worldbank.org - February 24, 2015

In an effort to measure the economic impact of Ebola on Liberian households, the World Bank, with the Liberian Institute of Statistics and Geo-Information Services and the Gallup Organization, has conducted four rounds of mobile-phone surveys, in October, November, December 2014 and January 2015.

CLICK HERE - The World Bank - The Socio-Economic Impacts of Ebola in Liberia

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Quick Test for Ebola - MIT

submitted by George Hurlburt

      

A new paper diagnostic device can detect Ebola as well as other viral hemorrhagic fevers in about 10 minutes. The device (pictured here) has silver nanoparticles of different colors that indicate different diseases. On the left is the unused device, opened to reveal the contents inside. On the right, the device has been used for diagnosis; the colored bands show positive tests.  Photo - Jose Gomez-Marquez, Helena de Puig, and Chun-Wan Yen

Simple paper strip can diagnose Ebola and other fevers within 10 minutes

CLICK HERE - Lab on a Chip - Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Massachusetts Institute of Technology (MIT) - eurekalert.org - February 24, 2015

CAMBRIDGE, MA -- When diagnosing a case of Ebola, time is of the essence. . .

. . . A new test from MIT researchers . . . The device, a simple paper strip similar to a pregnancy test, can rapidly diagnose Ebola, as well as other viral hemorrhagic fevers such as yellow fever and dengue fever. . .

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Limited Promise in early results from Ebola drug trial

AFP                                                                                                                     Feb. 23, 2015
Los Angeles  - Early results from an Ebola trial using the experimental drug Avigan (favipiravir) showed Monday it was somewhat effective at saving lives if given early in the illness, but not later.

Early results from an Ebola trial using the experimental drug Avigan (favipiravir) show it is somewhat effective at saving lives if given early in the illness (AFP Photo/George Frey)

The antiviral treatment is being developed by the Japanese company Toyama Chemical, and has been shown safe and effective against some other viruses including influenza, West Nile and yellow fever.

An ongoing clinical trial in Guinea is testing the drug's use in patients with the Ebola virus, which causes severe vomiting, diarrhea and sometimes fatal bleeding.

Results from only 80 people are available so far, but they show that among those who received the drug early in their illness, 15 percent died of Ebola.

Read complete story.

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