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Ebola rapid diagnostic kit developed by UK scientists in Sierra Leone

Doctors says the kit, if approved by health authorities, could transform the admissions process with its capacity to deliver results within 20 minutes

THE GUARDIAN    by Lisa O'Carroll                              March 29, 2015

A rapid Ebola diagnostic kit similar to a pregnancy kit has been developed by British military scientists and NHS medics in Sierra Leone.

Health care workers prepare to entering a high risk zone at an Ebola virus clinic in Sierra Leone, where the diagnostic kit has been undergoing tests. Photograph: Michael Duff/AP

It can be administered at the bedside and return its first results within 20 minutes, slashing dramatically the normal 24-hour turnaround for lab results.

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Home> Health Guinea Deploys Police as Sierra Leoneans Flee Ebola Lockdown

ASSOCIATED PRESS  By CLARENCE ROY-MACAULAY AND BOUBACAR DIALLO                  March 28, 2015

FREETOWN, Sierre Leone --Guinea has deployed security forces to the country's southwest in response to reports that Sierra Leoneans are crossing the border to flee an Ebola lockdown intended to stamp out the deadly disease, an official said Saturday.

A team of Sierra Leone health workers walk as they look for people suffering from Ebola virus symptoms or people they can educate about the virus as their country enters a three day country wide lockdown on movement of people due to the Ebola virus in the city of Freetown, Sierra Leone, Friday, March. 27, 2015. Sierra Leone's 6 million people were told to stay home for three days, except for religious services, beginning Friday as the West African nation attempted a final push to rid itself of Ebola. (AP Photo/ Michael Duff) Close The Associated Press

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Liberia Recommends Ebola Survivors Practice Safe Sex Indefinitely

THE NEW YORK TIMES  by Sheri Fink                                                                          March 29, 2015

The Liberian government recommended on Saturday that survivors of Ebola practice safe sex indefinitely, until more information can be collected on the length of time the virus might remain present in body fluids including semen. Previously, male survivors were advised to abstain from sexual intercourse or to use condoms for three months, reflecting that the active virus had been detected for up to 82 days in semen.

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Police fire tear gas on crowd during Sierra Leone Ebola lockdown

REUTERS by Josephus Olu-Mammah and Umaru Fofana                                                              March 28, 2015
FREETOWN, Sierra Leone --Police fired tear gas at an angry crowd in Sierra Leone on Saturday after they threw stones at officials during a three-day national lockdown that the government hopes will accelerate the end of the Ebola epidemic, residents said.

Sierra Leone has reported nearly 12,000 Ebola cases and more than 3,000 deaths since the worst epidemic in history was detected in neighbouring Guinea a year ago. New cases have fallen sharply since a peak of more than 500 a week in December but the government says the lockdown, its second, is necessary to identify the last cases and to buck a worrying trend towards complacency.

Officials have ordered the six million residents to stay inside on pain of arrest as hundreds of health official go door-to-door looking for hidden patients and educating residents about the haemorrhagic fever.

Hundreds of people left their homes in the Devil Hole neighbourhood outside the capital to gather at a food collection point. Some residents complained they had not received food and fighting broke out until police arrived to scatter the crowd.

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Combatting Rumors About Ebola: SMS Done Right

When misinformation is a case of life or death, aid workers and communities need an ear to the ground

INTERNEWS   by  Anahi Ayala Iacucci                                                March 26, 2015

 What is now clear to healthcare organizations working on the ground in West Africa is that the Ebola epidemic has been driven as much by misinformation and rumors as by weaknesses in the health system. It is common sense that information is a critical element in combatting disease, particularly when contagion from common social practices, such as bathing the corpses of the deceased, were central to so much of the early spread of the disease. But in the context of a massive disease outbreak, when hundreds of international organizations and billions of dollars flood into a region whose fragile infrastructure has been damaged by years of civil war, information dissemination becomes a powerful challenge.

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The State of Vaccine Confidence

The Vaccine Confidence Project    2015
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE 

Lead Authors:  Heidi Larson, PhD and Will Schulz, MPH
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Ebola crisis points to wider global threat on a par with al-Qaida, warns UK medic

THE GUARDIAN by Lisa O'Carroll                                                           March 27, 2015

Ebola should be seen as an early wake-up call to world leaders of the potential for an international health disaster in the same way that the 1998 US embassy bombings highlighted the possibility of further attacks by al-Qaida, a leading British medic in Sierra Leone has warned.

Dr Oliver Johnson has called for “a big political shakeup” at the World Health Organisation and says Britain’s Department for International Development must decide whether to “nationalise” aid and deploy the army the next time a humanitarian emergency hits.

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The tail of the epidemic and the challenge of tracing the very last Ebola case

EUROSURVEILLANCE  by  K. Kaasik-Aaslav and  D. Coulombier                                   March 26, 2015

Upon entering what seems to be the tail of the epidemic and, as in any such moment, the ‘Ebola endgame’ strategy requires adaptation to the heterogeneity of the epidemiological situation. The tools for EVD control need to be fine-tuned and the commitment from the teams supporting local authorities in affected countries needs to be sustained.

While the pressure on clinical and laboratory expertise gradually decreases, the demand shifts towards field epidemiologists to assist local public health experts and support community workers to engage in active surveillance and to monitor remaining transmission chains in affected communities.

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Laboratory support during and after the Ebola virus endgame: towards a sustained laboratory infrastructure

EUROSURVEILLANCE by I. Goodfellow, C. Reusken, and M. Koopmans  

  March 26, 2015                                                              

The Ebola virus epidemic in West Africa is on the brink of entering a second phase in which the (inter)national efforts to slow down virus transmission will be engaged to end the epidemic. The response community must consider the longevity of their current laboratory support, as it is essential that diagnostic capacity in the affected countries be supported beyond the end of the epidemic.

The emergency laboratory response should be used to support building structural diagnostic and outbreak surveillance capacity.

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Scientists argue over access to remaining Ebola hotspots

The slowdown in the West African Ebola epidemic is welcome news and reason to be hopeful—but it’s also creating a new problem. With fewer new cases occurring, it is becoming more and more difficult to test vaccines and drugs. As a result, conflicts are looming over who can test Ebola drugs and vaccines in Guinea and Sierra Leone.

An Ebola treatment unit in Guinea.Samuel Hanryon/MSF

In Guinea, a large consortium that includes Doctors Without Borders (MSF) and the World Health Organization (WHO) vaccinated the first volunteers at risk of Ebola on Monday in a big trial of a vaccine produced by Merck and NewLink Genetics. But the team feels threatened because researchers at the U.S. National Institutes of Health (NIH) are looking to move another vaccine study from Liberia, where the epidemic has come to a virtual standstill, to Guinea.

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