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Aid workers racing to defeat Ebola before the rains come

Sat, 2015-03-28 13:48 — mike kraft

USA TODAY by Samwar Fallah and Gregg Zoroya March 28, 2015

MONROVIA, Liberia — Aid workers are rushing into neighboring Guinea to try to stanch a worrisome rise in cases of the deadly Ebola virus, which has been slowed in Sierra Leone and been all but eradicated here.

A man crouches next to the grave of an unknown man (L) at the National Memorial Cemetry on Disco Hill, Margibi County, Liberia, 11 March 2015. The cemetery was established to provide a dignified burial for ebola victims and bring an end to the usual cremation of victims during the outbreak. Liberia on 11 March observed a National Memorial Day to remember, honour, and decorate the graves of the dead. The government of Liberia on 05 March discharged the last ebola patient, thus raising the hopes of the end of the epidemic. EPA/AHMED JALLANZO ORG XMIT: MON107(Photo: AHMED JALLANZO, EPA)

The mission is urgent because the coming rainy season could hamper travel to remote villages where the disease continues to emerge.

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The tail of the epidemic and the challenge of tracing the very last Ebola case

Sat, 2015-03-28 00:53 — mike kraft

EUROSURVEILLANCE by K. Kaasik-Aaslav and D. Coulombier March 26, 2015

Upon entering what seems to be the tail of the epidemic and, as in any such moment, the ‘Ebola endgame’ strategy requires adaptation to the heterogeneity of the epidemiological situation. The tools for EVD control need to be fine-tuned and the commitment from the teams supporting local authorities in affected countries needs to be sustained.

While the pressure on clinical and laboratory expertise gradually decreases, the demand shifts towards field epidemiologists to assist local public health experts and support community workers to engage in active surveillance and to monitor remaining transmission chains in affected communities.

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Laboratory support during and after the Ebola virus endgame: towards a sustained laboratory infrastructure

Fri, 2015-03-27 19:05 — mike kraft

EUROSURVEILLANCE by I. Goodfellow, C. Reusken, and M. Koopmans

March 26, 2015

The Ebola virus epidemic in West Africa is on the brink of entering a second phase in which the (inter)national efforts to slow down virus transmission will be engaged to end the epidemic. The response community must consider the longevity of their current laboratory support, as it is essential that diagnostic capacity in the affected countries be supported beyond the end of the epidemic.

The emergency laboratory response should be used to support building structural diagnostic and outbreak surveillance capacity.

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Two experimental Ebola vaccines pass safety test in African trial

Fri, 2015-03-27 14:03 — mike kraft

REUTERS by Sharon Begley March 26, 2015

NEW YORK - Two experimental Ebola vaccines, one from GlaxoSmithKline PLC and the other from biotech start-up NewLink Genetics Corp, "appear to be safe" part way through a clinical trial being conducted in Liberia, the U.S. National Institutes of Health (NIH) said on Thursday.

The two vaccines, each given in a single injection, are being tested for safety and efficacy on more than 600 people in Liberia in a mid-stage clinical trial sponsored by the National Institute of Allergy and Infectious Diseases, a branch of NIH.

The Ebola epidemic that began in West Africa one year ago has killed more than 10,200 people, but a decline in new cases in the most affected countries, Liberia, Guinea and Sierra Leone, has led to hopes that it may be ending.

Based on the encouraging safety results, the study may now advance to the next phase of efficacy testing, in which additional volunteers are injected with the GSK vaccine, the NewLink vaccine, or a dummy shot and assessed to see whether their immune system responds by producing anti-Ebola antibodies.

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How Did Ebola Volunteers Know Where To Go In Liberia? Crowdsourcing!

Thu, 2015-03-26 13:04 — mike kraft

NATIONAL PUBLIC RADIO by Poncie Rutsch March 25, 2015
From more than 900 miles away, Kpetermeni Siakor helped get volunteers to the right neighborhoods in his native Liberia during the height of the Ebola epidemic.

Kpetermeni Siakor (left), a Liberian who is studying in Ghana, used crowdsourcing software to help out during the Ebola epidemic. Courtesy of Ashesi University College

He did it with Ushahidi, crowdsourcing software that was developed in Kenya in 2008, when the country experienced a wave of post-election violence. The word Ushahidi means testimony in Swahili.

"The government had shut down internet connections and radio stations, so Ushahidi was born out of the need to let people know what is happening," says Siakor, 26. He's a computer science student at Ashesi University College in Accra, Ghana, and receives financial support from the MasterCard Foundation Scholars Program.

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Dr. Gavin Macgregor-Skinner - Ebola - Health Organizations Slow to Respond

Thu, 2015-03-26 12:55 — Kathy Gilbeaux

CLICK HERE - RECORDED VIDEO - Dr. Gavin Macgregor-Skinner

ctvnews.ca - March 23, 2015

Public health emergency expert Dr. Gavin Macgregor-Skinner discusses a new report saying faster action would have stopped the spread of Ebola.

CLICK HERE - MSF REPORT AND RELATED INFORMATION

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Ebola Vaccine Trial Starts in Guinea

Thu, 2015-03-26 12:48 — mike kraft

TIME MAGAZINE by Alexandra Sifferlin March 25, 2015
An efficacy trial for an Ebola vaccine launched in Guinea on Wednesday.

A health worker prepares a vaccination on March 10, 2015 at a health center in Conakry during the first clinical trials of the VSV-EBOV vaccine against the Ebola virus.

The vaccine, VSV-EBOV, was developed by the Public Health Agency of Canada and has already shown positive results in smaller safety trials. NewLink Genetics and Merck are collaborating on the vaccine, and the Guinean government and World Health Organization (WHO) are leading the trial, which is taking place in Basse-Guinée, a community where many Ebola cases spread.

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Fighting cancer and Ebola with nanoparticles

Wed, 2015-03-25 21:22 — mike kraft

CNN by Peter Shadbolt March 25, 2015

In medicine, finding a substance that attacks cancerous tumors without destroying the healthy tissue around it has long been the Holy Grail.

From targeted remedies such as monoclonal antibodies to surgery, cancer has still managed to elude a treatment that discretely and separately attacks it alone.

Nanotechnologies, however - the manipulation of matter at a molecular and even atomic scale to penetrate living cells -- are holding out the promise of opening a new front against deadly conditions from cancer to Ebola.

According to Dr Thomas Webster, the chair of chemical engineering at Northeastern University in Boston, research into medical nanotechnology is gaining pace and the medical establishment is starting to sit up and pay attention.

Read complete story.

http://www.cnn.com/2015/03/25/tech/webster-nanoparticles-cancer-mci/

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Fighting cancer and Ebola with nanoparticles

Wed, 2015-03-25 21:21 — mike kraft

CNN by Peter Shadbolt March 25, 2015

In medicine, finding a substance that attacks cancerous tumors without destroying the healthy tissue around it has long been the Holy Grail.

From targeted remedies such as monoclonal antibodies to surgery, cancer has still managed to elude a treatment that discretely and separately attacks it alone.

Nanotechnologies, however - the manipulation of matter at a molecular and even atomic scale to penetrate living cells -- are holding out the promise of opening a new front against deadly conditions from cancer to Ebola.

According to Dr Thomas Webster, the chair of chemical engineering at Northeastern University in Boston, research into medical nanotechnology is gaining pace and the medical establishment is starting to sit up and pay attention.

Read complete story.

http://www.cnn.com/2015/03/25/tech/webster-nanoparticles-cancer-mci/

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