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Low-cost portable device that can detect Ebola

Researchers have developed a low-cost and portable diagnostic device that can be used to detect Ebola infection and many other diseases. The device could be particularly useful to monitor endemic, epidemic and pandemic disease outbreaks in resource-limited developing countries that need portable diagnostic equipment that functions outside the hospital.

Read more at: http://www.oneindia.com/international/low-cost-portable-device-that-can-detect-ebola-2020618.html

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Ebola crisis provides framework for responding to outbreaks like Zika virus

As world leaders grapple with containing the Zika virus, the Ebola epidemic in West Africa provides valuable lessons for how to respond to other infectious disease epidemics, according to a policy report published by researchers at Princeton University and the Wellcome Trust.  

Rebuilding local health care infrastructures, improving capacity to respond more quickly to outbreaks and considering multiple perspectives across disciplines during decision-making processes are among the key recommendations the authors propose. 

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Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak

Antibodies targeting the Ebola virus surface glycoprotein (EBOV GP) are implicated in protection against lethal disease, but the characteristics of the human antibody response to EBOV GP remain poorly understood. We isolated and characterized 349 GP-specific monoclonal antibodies (mAbs) from the peripheral B cells of a convalescent donor who survived the 2014 EBOV Zaire outbreak. Remarkably, 77% of the mAbs neutralize live EBOV, and several mAbs exhibit unprecedented potency. Structures of selected mAbs in complex with GP reveal a site of vulnerability located in the GP stalk region proximal to the viral membrane. Neutralizing antibodies (NAbs) targeting this site show potent therapeutic efficacy against lethal EBOV challenge in mice. The results provide a framework for the design of new EBOV vaccine candidates and immunotherapies.

(complet article)

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WHO statement on end of Ebola flare-up in Sierra Leone

WHO joins the government of Sierra Leone in marking the end of the recent flare-up of Ebola virus disease in the country. As of today, 17 March, 42 days have passed, two incubation cycles of the virus, since the last person confirmed to have Ebola virus disease in the country tested negative for a second time.

This latest flare-up of Ebola brings to 3 590 the number of lives lost in Sierra Leone to an epidemic that devastated families and communities across the country and disrupted every aspect of life.

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To Prevent The Next Plague, Listen To Boie Jalloh

When Dr. Boie Jalloh got the call to join the fight against Ebola in Sierra Leone, his friends told him he'd be crazy to sign on. It's a good thing he didn't listen. Aurelie Marrier Dunienville for NPR

Image: When Dr. Boie Jalloh got the call to join the fight against Ebola in Sierra Leone, his friends told him he'd be crazy to sign on. It's a good thing he didn't listen. Aurelie Marrier Dunienville for NPR

npr.org - October 8th 2015 - Amy Maxmen

This is a landmark week in West Africa. For the first time since the Ebola outbreak, there were no new cases reported in Guinea, Liberia and Sierra Leone.

There are many unsung heroes who deserve credit for this milestone. 

(VIEW COMPLETE ARTICLE)

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How The Department of Defense Helped Confront Ebola

GEORGETOWN PUBLIC POICY REVIEW by Col.Russell E. Coleman   Aug. 12, 2015
WASHNGTON -- More than 10,000 people have died of Ebola virus disease (EVD) since the outbreak in West Africa began in December 2013. An epidemic of this magnitude, whether naturally occurring or caused by a biowarfare agent, could compromise both the U.S. health care system and the U.S. military’s ability to defend this country and its allies.


This possibility, long recognized by the Department of Defense (DoD), drives the department’s development of medical countermeasures. The response to the current Ebola outbreak demonstrates how DoD prepares for a medical threat without knowing (1) where it will happen, (2) when it might happen, (3) what the disease will be, and (4) what local resources will be immediately available.

Read complete article.
http://gppreview.com/2015/08/12/how-the-department-of-defense-helped-confront-ebola/

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China to build highway for Liberia as part of Ebola recovery aid

REUTERS                                                                                                  Aug. 9, 2015

MONROVIA -- China will build a new coastal highway for Liberia as part of its aid to the country recovering from an Ebola epidemic, Liberia's foreign minister said on Sunday.

He was speaking at a news conference with China's Foreign Minister Wang Yi who is visiting Liberia, Guinea and Sierra Leone, the countries hardest hit by the epidemic.

Liberia's existing coastal route is vital for commerce as the country rebuilds after a civil war that ended in 2003. It connects the capital to the border with Ivory Coast via the port city of Buchanan, where exports of exports of iron and timber pass through, but much of the road is unpaved.

Read complete story.
http://www.reuters.com/article/2015/08/09/us-health-ebola-liberia-china-idUSKCN0QE0OV20150809

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WHITE HOUSE FACT SHEET: The Global Health Security Agenda

The U.S. Government announces it intends to invest more than $1 billion in resources to expand the Global Health Security Agenda to prevent, detect, and respond to future infectious disease outbreaks overseas.

THE WHITE HOUSE PRESS OFFICE                       July 28, 2015

The Ebola epidemic in West Africa continues to galvanize global attention and resources as the international community strives to eliminate active cases and help the affected countries recover.  African leaders and African Union officials have shown extraordinary leadership in addressing the outbreak. The epidemic highlighted the urgent need to establish global capacity to prevent, detect, and respond to biological threats – to prevent future outbreaks from becoming epidemics. 

Beginning with the release of the National Strategy for Countering Biological Threats in 2009, and outlined in his 2011 speech at the United Nations General Assembly, President Obama has called upon all countries to come together to prevent, detect, and respond to infectious disease threats, whether naturally occurring, accidental or deliberately spread.  Today, the President underscored the unwavering U.S. commitment to partnering with Africans, their governments, and all who will join the effort to improve health security across the continent and for all people.

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Ebola created a public health emergency—and we weren’t ready for it

Could the international community have done a better job when confronted with the outbreak of Ebola in West Africa? Although the virus appears to be largely contained now, this comes after at least 27,000 people were infected, with 11,000 of them dying. The virus also had the opportunity to spread within the human population for over a year, providing it a potentially dangerous opportunity to adapt to us as hosts.

To find out whether we could have managed the outbreak better, the World Health Organization (WHO) recently convened an Ebola Interim Assessment Panel, which analyzed various aspects of the organization’s response. This panel, commissioned by the WHO Director-General, included the Dean of the Harvard School of Public Health, the founding Director of the UK's national Health Service, and other international public health leaders. It recently released its final report on the crisis.

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Ban to convene international Ebola recovery conference in New York

UN NEWS CENTRE                                                                                June 2, 2015

To help mobilize needed resources “in the last mile of the response” against the Ebola outbreak and to start the affected West African countries on the path of early recovery, United Nations Secretary-General Ban Ki-moon today announced that he will convene an international conference next month.
In Sierra Leone, local health workers plan for the day ahead, as they continue their vigilance against Ebola. Photo: WHO/S. Aranda

“All of your investments, all of the sacrifices and lives lost, and all of the risks that the relief workers took would be squandered if the outbreak recurs,” Mr. Ban cautioned in his remarks to an informal plenary of the UN General Assembly on the Organization’s Ebola response efforts.

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