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Health - West Africa MPHISE

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This working group is focused on discussions about health within the West Africa MPHISE.

The mission of this working group is to focus on discussions about health within the West Africa MPHISE.

Members

evakee John.R.Falco.VMD Kathy Gilbeaux mdmcdonald MDMcDonald_me_com

Email address for group

health_westafrica_mphise@m.resiliencesystem.org

This is How We Got to Zero Ebola Cases in West Africa:

whitehouse.gov - by Amy Pope - December 30, 2015

Summary: The world has now gone over 40 consecutive days without a single reported Ebola case. Here's how we helped make that possible.

For the first time since this outbreak was detected in West Africa in early 2014, the world has now gone over 40 consecutive days without a single reported Ebola case.

The World Health Organization (WHO) announced that Guinea has successfully halted Ebola transmission and now joins Sierra Leone and Liberia in recovering from this devastating disease. This represents a significant milestone for Guinea, West Africa, and the international community.

Today we reflect on what is possible when partners around the world come together to solve a common problem. Through the undaunted courage of local communities and heroes from around the world, West Africa was able to halt Ebola. The United States was proud to offer help along with partners around the world.

Today we remember Ebola’s victims, and embrace the communities, families, healthcare workers, and survivors.

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Quantifying Poverty as a Driver of Ebola Transmission

                                                  

journals.plos.org - Fallah MP, Skrip LA, Gertler S, Yamin D, Galvani AP (2015) Quantifying Poverty as a Driver of Ebola Transmission.
December 31, 2015 - PLoS Negl Trop Dis 9(12): e0004260. doi:10.1371/journal.pntd.0004260

Abstract

Background

Poverty has been implicated as a challenge in the control of the current Ebola outbreak in West Africa. Although disparities between affected countries have been appreciated, disparities within West African countries have not been investigated as drivers of Ebola transmission. To quantify the role that poverty plays in the transmission of Ebola, we analyzed heterogeneity of Ebola incidence and transmission factors among over 300 communities, categorized by socioeconomic status (SES), within Montserrado County, Liberia.

CLICK HERE - Quantifying Poverty as a Driver of Ebola Transmission

 

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Guinea’s Ebola Outbreak is Declared Officially Over

submitted by George Hurlburt / Mike Kraft

An MSF health worker holds baby Nubia Souma, the last known Ebola patient in Guinea.  Image: Samuel Aranda/MSF

CLICK HERE - WHO - STATEMENT - End of Ebola transmission in Guinea

(ALSO SEE SITUATION REPORTS AND RELATED ARTICLE BELOW)

Forty-two days have passed since the last person with Ebola tested negative for the virus.

thejournal.ie - by Sinead O'Carroll - December 29, 2015

THE WORLD HEALTH Organisation has declared the Ebola outbreak in Guinea officially over.

In a statement this morning, the global body confirmed that 42 days had passed since the last person with Ebola in the country tested negative for the virus for a second time.

Guinea will now enter a 90-day period of “heightened surveillance” to ensure any new cases are identified before being passed on to other people.

(READ COMPLETE ARTICLE)

(CLICK HERE - SEE RELATED ARTICLE)

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A New Weapon in Fight Against Ebola

The team has achieved an unprecedented goal: connecting 12 fullerenes, each one endowed with 10 sugar moieties, to other central fullerene, thus mimicking the presentation of carbohydrates surrounding the Ebola virus.  Credit: N. Martín & B. Illescas / UCM

CLICK HERE - A giant fullerene system inhibits the infection by an artificial Ebola virus

CLICK HERE - STUDY - Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection

scitechconnect.elsevier.com - by SPLICE - November 19, 2015

A discovery which may lead to the elimination of Ebola infections was published in Nature Chemistry a few days ago. The investigators reported that giant fullerene system inhibits the cell infection by an artificial Ebola virus.

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Is Ebola Virus One-Up Against Bats?

submitted by George Hurlburt      

         

CLICK HERE - STUDY - Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

socialnews.xyz - December 24, 2015

Ebola virus and bats have been waging a molecular battle for survival that may have started at least 25 million years ago, revealed a new study led by an Indian-origin scientist.

The findings shed light on the biological factors that determine which bat species may harbour the virus between outbreaks in humans and how bats may transmit the virus to people. . . .

. . . The study was published online in the journal eLife.

(READ COMPLETE ARTICLE)

 

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WHO Publishes List of Top Emerging Diseases Likely to Cause Major Epidemics

              

WHO Strategic Health Operations Centre (SHOC) Room - WHO /Christopher Black

who.int

A panel of scientists and public health experts convened by WHO met in Geneva this week to prioritise the top five to ten emerging pathogens likely to cause severe outbreaks in the near future, and for which few or no medical countermeasures exist. These diseases will provide the basis for work on the WHO Blueprint for R&D preparedness to help control potential future outbreaks.

The initial list of disease priorities needing urgent R&D attention comprises: Crimean Congo haemorrhagic fever, Ebola virus disease and Marburg, Lassa fever, MERS and SARS coronavirus diseases, Nipah and Rift Valley fever. The list will be reviewed annually or when new diseases emerge.

(READ COMPLETE ARTICLE)

ALSO SEE RELATED ARTICLE HERE - The most dangerous pathogens, according to WHO

 

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We’ve Learnt Many Lessons from This Outbreak and From the Response – Dr. David Nabarro, Special Envoy on Ebola

          

Dr. David Nabarro, Special Envoy on Ebola, at a press conference in New York in November 2015. UN Photo/Loey Felipe

un.org

10 December 2015 – In August 2014, amid a rapidly growing outbreak of Ebola, Dr. David Nabarro was tasked with providing strategic guidance for an enhanced international response, and galvanizing essential support for affected communities and countries. As the Secretary-General’s Special Envoy on Ebola, Dr. Nabarro played a key role in responding to the outbreak, which mainly affected Guinea, Liberia and Sierra Leone, and claimed more than 11,300 lives to date.

While the Ebola outbreak in West Africa has declined significantly in recent months, it is not completely over, making it all the more vital for everyone involved in the response to remain vigilant and focused on stopping the outbreak, staying at zero cases and preventing re-emergence. The Office of the Special Envoy will end its mandate on 31 December 2015, but the UN system will continue to remain fully engaged with the affected countries. 

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Liberia’s Ebola Outbreak Largely Traced to One Source

            

BRANCHING OUT  In Liberia, a single lineage of Ebola virus (middle dot) split into subgroups as it passed from person to person and mutated. Each dot is a slightly different version of the virus within the subgroups. Dot size indicates how many people carried that version. Researchers tracked the virus as it spread from Liberia (blue) into Guinea (red) and Mali (yellow).  J.T. Ladner et al/Cell Host & Microbe 2015

CLICK HERE - STUDY - Evolution and Spread of Ebola Virus in Liberia, 2014–2015

Genetic analysis of third hard-hit country fills in gaps in virus’ spread and evolution

sciencenews.org - by Tina Hesman Saey - December 9, 2015

A single introduction of the Ebola virus led to most cases of the deadly disease in Liberia, a new genetic study suggests.

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Stopping Ebola in its Tracks: a Community-Led Response

reliefweb.int - globalcommunities.org - December 1, 2015

The public view of the Ebola response was dominated by images and stories of medical workers and Ebola treatment units. But there is also the less-known story of the many thousands of Liberian health workers, government staff, traditional leaders and volunteers who played the most significant role in building resilience to Ebola and reducing transmission and infection. It is these groups, working in the frontlines and at significant risk, which Global Communities partnered with throughout the Ebola response.

Global Communities’ approach to countering the Ebola outbreak has been highlighted by President Obama, Dr. Rajiv Shah, former Administrator of USAID, and many others as having been a key component in the successful fight against Ebola in Liberia in the 2014-15 outbreak. This new publication “Stopping Ebola in its Tracks,” has two strands:

It describes Global Communities’ community-driven response to the Ebola outbreak in Liberia

It derives from this experience lessons learned and recommendations for preventing and dealing with future disasters

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Disease Specialists Identify Post-Ebola Threats

             

The West Africa Ebola outbreak has led experts to consider what diseases might spark the next major infectious disease crisis. Waldo Swiegers/Bloomberg via Getty Images

Scientists to assemble a rogues’ gallery of viruses likely to spark the next international public-health crisis

nature.com - by Erika Check Hayden - December 7, 2015 - doi:10.1038/nature.2015.18952

As West Africans try to bring the calamitous Ebola outbreak to an end, the World Health Organization (WHO) has called scientists and doctors to Geneva, Switzerland, on 8 and 9 December to discuss which infectious disease is likely spark the next pandemic. . . 

. . . Nature canvassed infectious-disease specialists to find out which pathogens they thought would trigger the next global crisis, and which treatments and vaccines might be readied to combat them.

(READ COMPLETE ARTICLE)

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