Health - West Africa MPHISE

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Mon, 2015-02-23 05:17 — mdmcdonald

This working group is focused on discussions about health within the West Africa MPHISE.

The mission of this working group is to focus on discussions about health within the West Africa MPHISE.

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A Chinese Ebola Drug Raises Hopes, and Rancor

Fri, 2015-06-12 14:25 — mike kraft

NEW YORK TIMES by Sheri Fink, MD June 12, 2015

After a nurse who contracted Ebola in Sierra Leone was discharged Wednesday from a Rome hospital, a doctor there described the experimental treatments the patient had received as “absolutely miraculous.”

The lab at Beijing Mabworks, which developed the experimental drug, MIL77, used to treat Ebola. Credit Adam Dean for The New York Times

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International Ebola Recovery Conference Ending Ebola: “Get to Zero, Stay at Zero and Rebuild”

Fri, 2015-06-12 01:50 — Maeryn Obley

Congo Town, Freetown, Sierra Leone. Photo: Dylan Lowthian/UNDP

Image: Congo Town, Freetown, Sierra Leone. Photo: Dylan Lowthian/UNDP

africa.undp.org - May 9th, 2015

United Nations Secretary-General Ban Ki-moon will host an International Ebola Recovery Conference in July to ensure that the affected countries receive the resources and support they need to overcome the wider socio-economic consequences of the ongoing Ebola outbreak.

The conference at United Nations Headquarters in New York on 10 July 2015 will take place in cooperation with the Governments of Guinea, Liberia and Sierra Leone, together with other partners.

With numbers of Ebola cases have dropped, the affected countries still need the support of the international community to get to zero cases, stay there, and to move forward on the road to recovery.

(VIEW COMPLETE ARTICLE)

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Ghana halts Ebola vaccine trial due to community protests

Thu, 2015-06-11 00:00 — mike kraft

REUTERS June 10, 2015

ACCRA - Ghana has halted a plan to test two Ebola vaccines in an eastern town after legislators backed local protests against the trials sparked by fears of contamination, officials said on Wednesday.

The country's Food and Drugs Authority said it had begun enlisting volunteers in Hohoe in the Volta region to be injected with drugs made by Johnson & Johnson and Bavarian Nordic as part of a global Ebola vaccine drive.

Youth leaders threatened to boycott the program. "We don't want to be guinea pigs," one local leader told Reuters.

The (health) minister has suspended the trials indefinitely because the people said they don't want it," Health Ministry spokesman Tony Goodman said.

Read complete article.

http://news.yahoo.com/ghana-halts-ebola-vaccine-trial-due-community-protests-230206801--finance.html;_ylt=AwrC1Cj8y3hVjHUAonXQtDMD;_ylu=X3oDMTByOHZyb21tBGNvbG8DYmYxBHBvcwMxBHZ0aWQDBHNlYwNzcg--

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Ebola Cases Rise Again in West Africa

Wed, 2015-06-10 23:17 — mike kraft

NBC NEWS by Magie Fox June 10, 2015

The steady decline in Ebolacases has stopped and the numbers are ticking up again in Guinea and Sierra Leone, the World Health Organization reported Wednesday.

WHO is worried that there are still people who don't understand how to stop the spread of the virus, which has infected more than 27,000 people and killed more than 11,000 of them in the West African epidemic. Even more worrying, it's not entirely clear where some of the new cases have come from....

If health workers can find out where and how people were infected, they can track down and check everyone who might have been in close contact and night transmit the disease. But there are still mysterious outbreaks.

Read complete story.
http://www.nbcnews.com/storyline/ebola-virus-outbreak/ebola-ticks-again-west-africa-n373171

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How Computer Modelers Took On the Ebola Outbreak

Wed, 2015-06-10 13:35 — Kathy Gilbeaux

submitted by Sarah Slaughter

At The Epidemic’s Epicenter: A Liberian child sits in an Ebola isolation ward housing people who might have contracted the contagious disease. Photo: John Moore/Getty Images

Did real-time epidemic modeling save lives in West Africa?

spectrum.ieee.org - by David Brown - May 28, 2015

. . . “agent-based” models will give a more nuanced picture of how pathogens affect and sicken a population. “This is the wave of the future,” says Stephen Eubank, deputy director of the Virginia Tech lab. “It’s going to take a concerted effort to gather the data and the expertise. But it’s going to happen.”

And so, too, will another Ebola outbreak.

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GSK, Johnson & Johnson behind Ebola vaccine trial in Ghana

Tue, 2015-06-09 15:22 — mike kraft

Controversy over Vaccine trials in Ghana

GHANAWEB.COM June 9, 2015

Leading pharmaceutical companies including Johnson & Johnson, Bavarian Nordic, the Public Health Agency of Canada (PHAC) and GlaxoSmithKline (GSK) are the companies behind the impending Ebola vaccine trial in Ghana....

Ghana's Food and Drugs Authority (FDA) on Monday confirmed that vaccines for Ebola would be tested in Ghana, but dismissed reports that the trial will harm persons who will be used as ‘guinea pigs’ for the exercise....

StarrFMonline.com sources revealed that the Hohoe Midwifery Training School has been selected for the project. As part of an enticement package, students who volunteer for the trial will be given Ghc200 and a cell phone as reward.

Several civil society organisations including the Ghana Academy of Arts and Sciences, Coalition for Ghana’s Independence Now (CGIN) and the Volta regional branch of the ruling NDC have all kicked against the exercise and called on government to stop the trial immediately.
Read complete story.

http://www.ghanaweb.com/GhanaHomePage/NewsArchive/artikel.php?ID=361643

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Ebola Virus Disease Outbreak in Nigeria: Transmission Dynamics and Rapid Control

Sun, 2015-06-07 03:41 — Kathy Gilbeaux

ncbi.nlm.nih.gov - Epidemics. 2015 Jun;11:80-4. doi: 10.1016/j.epidem.2015.03.001. Epub 2015 Mar 21

Abstract

International air travel has already spread Ebola virus disease (EVD) to major cities as part of the unprecedented epidemic that started in Guinea in December 2013. An infected airline passenger arrived in Nigeria on July 20, 2014 and caused an outbreak in Lagos and then Port Harcourt. After a total of 20 reported cases, including 8 deaths, Nigeria was declared EVD free on October 20, 2014. We quantified the impact of early control measures in preventing further spread of EVD in Nigeria and calculated the risk that a single undetected case will cause a new outbreak. We fitted an EVD transmission model to data from the outbreak in Nigeria and estimated the reproduction number of the index case at 9.0 (95% confidence interval [CI]: 5.2-15.6). We also found that the net reproduction number fell below unity 15 days (95% CI: 11-21 days) after the arrival of the index case. Hence, our study illustrates the time window for successful containment of EVD outbreaks caused by infected air travelers.

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Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

Sun, 2015-06-07 03:01 — Kathy Gilbeaux

submitted by Denis Gilhooly

World Economic Forum
Prepared in collaboration with the Boston Consulting Group (BCG)

CLICK HERE - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

CLICK HERE - REPORT - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation
(20 page .PDF report)

The Ebola outbreak in West Africa was a public health emergency of new proportions that presented unprecedented challenges for the international community. Aside from the significant social and economic impact it had on many West African countries, the epidemic also triggered a range of innovative, flexible partnership responses from businesses and civil society that complemented the channels of official assistance to affected countries.

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The contribution of Ebola viral load at admission and other patient characteristics to mortality in a Médecins Sans Frontières (MSF) Ebola Case Management Centre (CMC), Kailahun, Sierra Leone, June –October, 2014

Sun, 2015-06-07 01:48 — Kathy Gilbeaux

m.jid.oxfordjournals.org - J Infect Dis. (2015) doi: 10.1093/infdis/jiv304 First published online: May 22, 2015

Abstract

This paper describes patient characteristics, including Ebola viral load, associated with mortality in an MSF Ebola case management centre.

Out of 780 admissions between June and October 2014, 525 (67%) were positive for Ebola with a known outcome. The crude mortality rate was 51% (270/525). Ebola viral load (whole blood sample) data was available on 76% (397/525) of patients. Univariate analysis indicated viral load at admission, age, symptom duration prior to admission and distance travelled to the CMC were associated with mortality (p value<0.05). The multivariable model predicted mortality in those with a viral load at admission greater than 10 million copies per millilitre (p value<0.05, Odds Ratio>10), aged 50 years or more (p value=0.08, Odds Ratio=2) and symptom duration prior to admission less than 5 days (p value=0.14). The presence of confusion, diarrhoea and conjunctivitis were significantly higher (p value<0.05) in Ebola patients who died.

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West Africa Struggles to Rebuild Its Ravaged Health-Care System

Sat, 2015-06-06 01:08 — mike kraft

WALL STREET JOURNAL by Betsy McKay June 4, 2015
HARPER, Liberia --The deadly disease may have receded, but it is still exacting a heavy toll. Run-down, poorly staffed and equipped health facilities allowed Ebola to explode.

Since it was identified in early 2014, the epidemic has claimed the lives of 507 health-care workers in three West African countries, all of which already were short of medical professionals. The health-care system was so overwhelmed with Ebola victims that many other patients couldn’t receive care for malaria, heart disease or pregnancy complications. That bill is coming due.

“There are more people who are going to die from Ebola, but not have Ebola,” says Paul Farmer, a Harvard professor and co-founder of the Boston-based charity Partners in Health.

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