Source:Centers for Disease Control and Prevention (CDC) - Date Published:08/20/2015

Annotation:This 38-page document provides a standard format for creating an Ebola Concept of Operations (ConOps) plan at the state, territorial, or major metropolitan area government level. It provides information on measures local governments, agencies, and organizations can take to support the plan. The ConOps in the template describes strategic, high-level considerations for establishing a regional tiered system to safely and effectively manage persons under investigation (PUIs) or patients confirmed with Ebola.

(38 page .PDF document)
URL: http://www.cdc.gov/phpr/documents/ebola-concept-of-operations-planning-template-8-20-2015.pdf

Authors:Dugas, Robert; Lamoureux, Joe; Mangieri, William; et al.
Type:Guideline/Assessment Tool
ID:11129. From Disaster LitTM, a database of the U.S. National Library of Medicine.

http://disasterlit.nlm.nih.gov/record/11129

VOICE OF AMERICA by James Butty  Sept. 2, 2015

 Sierra Leone Tuesday quarantined 50 people in the northern district of Kambia, where a 76 year-old woman died over the weekend from Ebola. The country had just celebrated the release from the hospital of its last known Ebola patient.

Read complete story.
http://www.voanews.com/content/sierra-leone-quarantines-50-following-latest-ebola-death/2941906.html

Ebolavirus, animal - Uganda: porcine, epidemiological assessment

CLICK HERE - Assessing the Potential Role of Pigs in the Epidemiology of Ebola Virus in Uganda

promedmail.org - September 2, 2015

Summary

Uganda has experienced 4 Ebola outbreaks since the discovery of the virus. Recent epidemiological work has shown pigs are hosts for ebolaviruses. Due to their high reproduction rates, rapid weight gain, potential to provide quick financial returns, and rising demand for pork, pig production in Uganda has undergone massive expansion. The combination of pork sector growth supported by development programmes and Ebola virus risk prompted a foresight exercise using desk, interview, and spatial methods. The study found that the lack of serological evidence for specific reservoir species, the number of human index cases unable to account for their source of infection, domestic pig habitat overlap with potential Ebola virus zoonotic host environments, reported interactions at the human-pig-wildlife interface that could support transmission, fever in pigs as a commonly reported problem by pig farmers, and temporal correlation of outbreaks with peak pork consumption periods, warrants further research into potential zoonotic transmission in Uganda from pigs.

thenewdawnliberia.com - by Ben P. Wesee - Editing by Jonathan Browne -September 1, 2015

The four Mano River Union or MRU countries – Liberia, Sierra Leone, Guinea and Ivory Coast have issued a joint communiqué in Monrovia, calling for information sharing, experiences and good practices during and after health emergencies in order to collaborate and network with local and international partners in the sub-region.

In a just ended conference here on the Ebola Virus Disease or EVD, the MRU countries also advanced several recommendations. Delegates from the four countries recommended in the communiqué a need to develop a harmonized framework for adherence to ethical standards during health disasters with appropriate and approved mechanisms for vaccines, therapeutic agents and testing methods.

(READ COMPLETE ARTICLE)

(ALSO SEE RELATED ARTICLE HERE)

Ebola Situation Reports:

CLICK HERE -  Interagency Collaboration on Ebola - Situation Report - 1 September 2015 (7 page .PDF report)

CLICK HERE - Report Archives - Interagency Collaboration on Ebola

Note:

The numbers of suspected Ebola cases have increased by 2 in Guinea, and by 6 in Sierra Leone per the Aug. 30 data as compared to the August 29 data.

August 30 data (Published September 1)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150901?lang=en

August 29 data (Published August 31)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150831?lang=en

CLICK HERE - RESEARCH - Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

prweb.com - by Cynthia Lujan - September 1, 2015

A new host-based therapy for Ebola, anthrax and other deadly infectious diseases has been discovered by researchers at the Keck Graduate Institute and its collaborators. The discovery has the potential to speed to market treatments for previously untreatable diseases.

The findings were published online on August 27 by Scientific Reports, an open access research journal from the publishers of Nature.

The lead authors of the story were Leoor Zilberminitz and William Leonardi, doctoral students in KGI laboratory of assistant professor Mikhail Martchenko. The researchers screened a library of 1,581 drugs previously approved by the FDA for in vitro protection of mammalian cells against Bacillus anthracis lethal toxin and diphtheria toxin, which normally kill 50-70% of unprotected cells. They then investigated the 1% most promising compounds that both provided the best protection against the two toxins and were not toxic to uninfected cells.

submitted by Gavin Macgregor-Skinner

SFCG’s Director Bloh (L) and participants of the workshop (R)

liberianobserver.com - by Joaquin Sendolo - August 31, 2015

The United States Agency for International Development (USAID) has provided US$290,000 through IREX to Search for Common Ground (SFCG) to sensitize communities on the negative impacts stigma makes on Ebola survivors.

Since the outbreak of the Ebola virus disease (EVD) in Liberia, those who survived the disease have reportedly suffered stigma in various communities, thus causing them to feel discriminated against.

The stigma comes about because of fear that survivors could still be transmit[ting] the virus when they are touched since it is one way of contracting EVD.

(READ COMPLETE ARTICLE)

usnews.com - Associated Press (AP) - by CLARENCE ROY-MACAULAY - August 30, 2015

FREETOWN, Sierra Leone (AP) — Health officials in Sierra Leone on Sunday confirmed an Ebola death less than a week after the country's last known patient was discharged from a hospital.

Samples from the body of a 67-year-old woman who died recently in Kambia district in the country's north came back positive for the deadly disease, said chief medical officer Dr. Brima Kargbo. . . .

. . . The National Ebola Response Center had deployed teams to conduct surveillance and trace people who were in contact with the woman, said OB Sisay, the center's director.

(READ COMPLETE ARTICLE)

allafrica.com - August 24, 2015

Freetown — The Guinean Ebola Ring Vaccine Trial has been extended to Sierra Leone as a move to stop the transmission across the region.

Addressing participants in the opening ceremony of the training session at the Brookfields Hotel Conference Hall in Freetown, the WHO Ebola Technical Coordinator Sierra Leone, Dr. Margaret Lamumu said prior to the extension of the vaccine to Sierra Leone the Ministry of Health and Sanitation and WHO Joint Team visited five sites to make available the vaccine study, adding that expert trainers from the UK were targeted to do the training. . . .

. . . The Chief Medical Officer, Dr. Brima Kargbo said the use of the vaccine would help break the chain of transmission, stressing the need to work collectively as a team to control the spread of the disease.

(READ COMPLETE ARTICLE)

(CLICK HERE - For Additional Information)

CDC - American Hospital Association - August 27, 2015

The Centers for Disease Control and Prevention today issued updated guidance regarding personal protective equipment for health care personnel caring for suspected and confirmed Ebola patients in U.S. health care facilities. The changes clarify the use of fluid-resistant and impermeable gowns and coveralls, and provide specifications to assist facilities in selecting and ordering the recommended garments. The updates also provide additional explanation related to PPE for confirmed Ebola patients. For more information, see the updated PPE Frequently Asked Questions.

http://news.aha.org/article/150827-cdc-updates-ebola-ppe-guidance-for-us-health-care-facilities

Ebola Situation Reports:

CLICK HERE -  Interagency Collaboration on Ebola - Situation Report - 25 August 2015 (7 page .PDF report)

CLICK HERE - WHO - Situation Report - 26 August 2015

CLICK HERE - Report Archives - Interagency Collaboration on Ebola

CLICK ON THE LINKS BELOW - Current - Report Archives - WHO
http://apps.who.int/ebola/ebola-situation-reports
http://apps.who.int/ebola/ebola-situation-reports-archive

CLICK ON THE LINK BELOW - Older Report Archives - WHO
http://www.who.int/csr/disease/ebola/situation-reports/archive/en/

Health care workers deemed at high risk for infection didn't get sick after treatment with anti-flu regimen

CLICK HERE - The Lancet - Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers

nlm.nih.gov - by Robert Preidt - August 25, 2015

Antiviral drugs may help protect people from developing Ebola after exposure to the deadly virus, a new case study suggests.

"We are excited to publish the first report of an antiviral-based post-exposure treatment against Ebola-virus infection in humans. We believe this work justifies further study of this postexposure treatment to protect health care workers accidentally exposed to Ebola virus in the field," lead author Dr. Michael Jacobs, of the Royal Free NHS Foundation Trust, London, said in a news release from The Lancet Infectious Diseases.

"What is more, a similar approach to treat household contacts of Ebola cases may work to prevent a major route of spread during an epidemic," he added.

(READ COMPLETE ARTICLE)

link.springer.com - EcoHealth - August 13, 2015 
Siv Aina J. Leendertz, Jan F. Gogarten, Ariane Düx, Sebastien Calvignac-Spencer, Fabian H. Leendertz

CLICK HERE - Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses

Introduction

Since their discovery 40 years ago, Ebola viruses (in the following: EBOV; family Filoviridae, genus Ebolavirus) continue to emerge unpredictably and cause Ebola virus disease (EVD) in humans and susceptible animals in tropical Africa (Leroy et al. 2004; Feldmann and Geisbert 2011). The scale of the current epidemic in West Africa demonstrates the impact that a single spillover event can have (Baize et al. 2014; Gire et al. 2014). Meanwhile, the reservoir(s) and ecology of EBOV remain largely unknown (Groseth et al. 2007; Feldmann and Geisbert 2011), hampering prediction of future outbreaks.

Mattia Panciroli / Flickr cc

CLICK HERE - WHO - First meeting of the Review Committee on the role of International Health Regulations in the Ebola response and WHO’s work in emergencies

cidrap.umn.edu - by Lisa Schnirring - August 25, 2015

A World Health Organization (WHO) committee tasked with reviewing how well the International Health Regulations (IHRs) worked during the Ebola outbreak wrapped up their first meeting today, with plans to dig into three main topics in the months ahead.

The group's newly elected chairman, Didier Houssin, MD, addressed reporters today during a telebriefing at the end of the 2-day meeting in Geneva. He is a surgeon who now heads the Evaluation Agency for Research and Higher Education in Paris. Houssin has served on WHO advisory groups before and has led some of its pandemic preparedness and IHR review groups in recent years.

(READ COMPLETE ARTICLE)

From WFP and FAO . . .

FAO – July 2015 – Food and nutrition situation at the beginning of the hunger gap period and agricultural outlook in the Sahel and West Africa (see number 5)
http://www.fao.org/emergencies/resources/documents/resources-detail/en/c/296696/

FAO – Sierra Leone – Food Security and Safety
http://www.fao.org/countryprofiles/index/en/?iso3=SLE&paia=2

FAO in Emergencies – Sierra Leone (see list of reports at the bottom)
http://www.fao.org/emergencies/countries/detail/en/c/161501/

FAO – Liberia – Food Security and Safety
http://www.fao.org/countryprofiles/index/en/?iso3=LBR&paia=2

FAO in Emergencies – Liberia (see list of reports at the bottom)
http://www.fao.org/emergencies/countries/detail/en/c/161431/