Africa

ASSOCIATED PRESS by JONATHAN PAYE-LAYLEH                                             March 5, 2015

MONROVIA -- Liberia released its last Ebola patient, a 58-year old English teacher, from a treatment center in the capital on Thursday, beginning its countdown to being declared Ebola free.

"I am one of the happiest human beings today on earth because it was not easy going through this situation and coming out alive," Beatrice Yardolo told The Associated Press after her release.

...The St. Paul's Bridge community where she resides and teaches had become the last "hotspot" for Ebola cases in Monrovia, according to Tolbert Nyenswah, Assistant Health Minister and head of the country's Ebola response.

Description of key Ebola areas---MSF

MSF                                                        March 3, 2015

The Ebola outbreak in West Africa continues, albeit with decreasing intensity. The virus has infected more than 23,700 people across the region since the outbreak was declared 11 months ago. While the number of new patients in Liberia is declining, numbers are still fluctuating in both Guinea and Sierra Leone. A total of 99 new confirmed cases were reported across the three worst affected countries during the week up to 22 February 2015.

The unpredictable nature of the epidemic means that teams from Médecins Sans Frontières/Doctors Without Borders (MSF) are maintaining a flexible approach and continuing to respond where the needs are greatest in Guinea, Liberia and Sierra Leone.

See country-by-country analysis and complete story.

http://www.msf.org/article/ebola-epidemic-not-over-%E2%80%93-key-areas-still-need-be-tackled

REUTERS by Adrian Croft                                                                                     March 3, 2015
BRUSSELS - The three West African states hardest hit by the Ebola outbreak asked for help from donors on Tuesday to repair the damage to their economies now that the epidemic seems to be waning.

Leaders of Guinea, Liberia and Sierra Leone voiced confidence at a major international conference on the Ebola outbreak in Brussels that they were winning the battle but said they must remain focused on stamping out new infections....

International donors have pledged nearly $5 billion to help combat the Ebola outbreak, according to EU officials, although only about half of that has been disbursed so far.....

 The World Bank has estimated the epidemic will cost the three countries at least $1.6 billion in lost economic growth this year, or more than 12 percent of their combined output.

Read complete story.

http://news.yahoo.com/ebola-hit-countries-seek-help-repair-economies-161332797.html;_ylt=AwrBJR6.3_VUSjIA7pzQtDMD

FORBES   by   David Kroll                                                                                          March 1, 2015

The widely-discussed antibody cocktail, ZMapp, is finally going to be tested under standardized, controlled conditions for its safety and efficacy in Ebola virus disease-infected patients in Liberia and, potentially, the United States.

Late Friday, the NIH National Institute of Allergy and Infectious Disease (NIAID) announced the launch of a randomized trial in up to 200 patient volunteers with confirmed Ebola virus infections.

The two-arm study will compare supportive standard of care with or without three intravenous infusions of ZMapp spaced three days apart. This is the same dosing regimen published in Nature that protected 18 of 18 monkeys when given up to five days after experimental infection.

LeafBio, the commercial arm of San Diego-based Mapp Biopharmaceutical, announced concomitantly that the FDA had approved their IND for this trial. The three antibodies that comprise ZMapp target both distinct and overlapping parts of the Ebola virus glycoprotein (GP) that it uses to infect humans.