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Lack of Ebola Cases Shifts Vaccine Trials Away From Liberia

TIME MAGAZINE  by Alexandra Sifferlin                                                                        March 13, 2015

The National Institutes of Health (NIH) may relocate its clinical trials of Ebola vaccines to Guinea, since there are no longer enough Ebola cases in Liberia for a proper efficacy trial.

On Feb. 2, the NIH launched an initial safety trial for two vaccines to protect against Ebola in Liberia. The plan was to test 600 people for overall safety and then launch a second phase of the trial in 27,000 people to see whether or not the vaccine prevents infection with Ebola virus compared to a placebo.

The safety test was successfully completed the week of March 9—but around the same time, Liberia announced that it had released its last confirmed patient from its Ebola treatment centers. ...

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The hidden cost of Ebola: thousands of measles deaths

VOX  by Julia Belluz                                            March 12, 2015

(Scroll down for full Science Journal study.)

As if being stricken by the most deadly virus known to man weren't enough, now, it seems, West Africa is on alert for outbreaks of vaccine-preventable diseases including measles, whooping cough, and tuberculosis.

A girl collects her family's laundry after drying it on a rooftop in the West Point township on January 31, 2015 in Monrovia, Liberia. Life has been disrupted by Ebola for many Liberians.

In a new study in the journal Science, researchers focused on measles — the most contagious virus recorded — and applied statistical models to quantify the likelihood of an epidemic in the three countries worst hit by Ebola, Liberia, Sierra Leone, and Guinea.

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The hidden cost of Ebola: thousands of measles deaths

VOX  by  Julia Belluz                                           March 12, 2015

(Scroll down for Science journal study.)

As if being stricken by the most deadly virus known to man weren't enough, now, it seems, West Africa is on alert for outbreaks of vaccine-preventable diseases including measles, whooping cough, and tuberculosis.

A girl collects her family's laundry after drying it on a rooftop in the West Point township on January 31, 2015 in Monrovia, Liberia. Life has been disrupted by Ebola for many Liberians.

In a new study in the journal Science, researchers focused on measles — the most contagious virus recorded — and applied statistical models to quantify the likelihood of an epidemic in the three countries worst hit by Ebola, Liberia, Sierra Leone, and Guinea.

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Ebola could cost West Africa $15 billion over three years

REUTERS  by Misha Hussain                                                    March 12, 2015sC

(Scroll down for links to press release and full report.)

DAKAR -- West Africa may lose up to $15 billion over the next three years due to the impact of the Ebola outbreak on trade, investment and tourism, according to a report by the United Nations.

The world's deadliest Ebola epidemic has killed almost 10,000 people in the three most affected countries of Guinea, Liberia and Sierra Leone, deepening poverty in one of the least developed parts of the world.

"The consequences of Ebola are vast," said Abdoulaye Mar Dieye, Africa director of the United Nations Development Programme (UNDP).

"Stigma and risk aversion have caused considerable amounts of damage, shutting down borders and indirectly affecting the economies of a large number of countries in the sub-region."

Read complete story

http://news.yahoo.com/ebola-could-cost-west-africa-15-billion-over-150805196.html;_ylt=AwrBJSCTtwFVoAIAda3QtDMD

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Study Indicates Ebola-Infected Sewage May Require Longer Holding Period

INFECTION CONTROL TODAY                                          March 11, 2015
Storing Ebola-infected sewage for a week at 86 degrees Fahrenheit or higher should allow enough time for more than 99.99 percent of the virus to die, though lower ambient temperatures may require a longer holding period, according to a new study by researchers at Georgia State University's School of Public Health.

The study co-authored by Lisa M. Casanova, assistant professor of environmental health, and Scott R. Weaver, research assistant professor in Epidemiology and Biostatistics, used bacteriophage Φ6, a type of virus, as a stand-in to study how long Ebola and similar viruses can survive in latrines and other systems for collecting and disposing of sewage. Bacteriophage Φ6 has a lipid envelope, meaning it has structural similarities to Ebola and several other types of virus, allowing for a safe study that did not require use of Ebola itself.

"The places hardest hit by Ebola are the places that often have the least infrastructure for safely disposing of sewage and are using things like pit latrines," says Casanova. "They need the answers to questions like this."

Read full article.

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Waning interest is biggest risk in race to overcome Ebola: WHO

REUTERS     by Tom Miles                                                                                        March 11, 2015

GENEVA -Waning interest in Ebola could jeopardize efforts to stamp out the world's worst recorded outbreak of the disease, the World Health Organization said on Wednesday.

Nameplates are seen at a cemetery for victims of Ebola virus in Suakoko, Liberia, March 11, 2015.  Reuters/James Giahyue

Case numbers have fallen to a low level and it should be possible to stop transmission by mid-year, but the disease is "not waning" and it is much too early to assume the outbreak will end, said WHO Assistant Director General Bruce Aylward.

"We talk often about how steep the drop in cases has been. The only thing that has dropped more quickly and more steeply is the new contributions in financing," he told reporters in Geneva. 

...the failure to make further inroads is "alarming", Aylward said.

"Getting from here to zero is going to require another reinvestment (in the drive to tackle the outbreak)."

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Ebola-Stricken Countries Lagged in Health Systems

savethechildren.org

CLICK HERE - REPORT - A WAKE-UP CALL - Lessons from Ebola for the world’s health systems (50 page .PDF report)

nytimes.com - by Donald G. McNeil Jr. - March 9, 2015

The world has spent more than $4 billion fighting Ebola, but according to a new report from Save the Children, it would have cost only $1.6 billion to bring health care systems up to minimum standards in Sierra Leone, Liberia and Guinea, which might have prevented the outbreak or ended it faster.

Even before Ebola struck West Africa, more than 25 countries had health care systems worse than those in impoverished Liberia and Sierra Leone, the report also found.

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Ebola is Still Here: Voices from Liberia and Sierra Leone on Response and Recovery

policy-practice.oxfam.org.uk - Authors: Cairns, Edmund
February 27, 2015 - ISBN: 978-1-78077-825-9

In Sierra Leone and Liberia, thousands of local people have taken part in campaigns to spread the message about how Ebola can be controlled, and millions have taken vital practical steps to prevent infection. When the last case of Ebola is eliminated, it will not only be because of medical treatment and action by governments and the international community, but because communities have been at the heart of the response. Before Ebola struck West Africa, Liberia and Sierra Leone were among the poorest countries in the world – now they are even poorer. The challenge of recovery is enormous and communities must once again be at the heart of it. Oxfam has listened to women and men in Liberia and Sierra Leone to hear their priorities for the immediate response, the recovery and beyond. This paper presents those priorities, from rebuilding shattered livelihoods and building a resilient health service, to making schools safe and free for all.

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Global Ebola Response Coalition Meeting (GERC) - 06 March 2015

                                                     

ebolaresponse.un.org

Coalition Meeting Notes - Minutes from the weekly meetings held by the Global Ebola Response Coalition:

Global Ebola Response Coalition Meeting 21 | 6th March 2015:

Issues Discussed and Next Steps

The twenty first meeting of the Global Ebola Response Coalition Core Group took place on 6 March. The main points covered in the meeting follow.

2.            Participants discussed the status of the outbreak.  The cumulative number of people who have been diagnosed with Ebola in the current outbreak is now 23,983. The number of people newly diagnosed with Ebola in the 7 days to 1 March, is 132; the figure was 99 in the preceding 7 days. This week’s total reflects increases in Guinea (35 to 51) and Sierra Leone (63 to 81) but a fall in Liberia (1 to 0). The volatility in numbers of people newly diagnosed with Ebola each week continues: the figure ranges between 90 and 160 new cases per week.  The majority of new cases are reported from the geographical region around the coastal border areas between Guinea and Sierra Leone.

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Economist: Some high-tech solutions fail with fight against Ebola in West Africa

THE ECONOMIST                                                                                                   March 9, 2015

As in all Ebola episodes, preventing infection in West Africa during what has been the worst outbreak in history has placed a lot of effort on looking after those dealing with the victims. New high-tech equipment is now available for use by health care workers, but in some countries it may be inappropriate....

Health care workers inside a USAID-funded Ebola clinic in Liberia wearing protective gear. Some of the best protective gear or technology is not available to African countries because of high costs or other conditions.  Photos by Abbas Dulleh • Associated Press,

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